THE INFLUENCE OF THE COMPOSITION OF INTESTINAL MICROBIOTA ON BIOCHEMICAL PARAMETERS IN PATIENTS WITH TYPE 2 DIABETES
Keywords:
Type 2 diabetes mellitus (T2DM) is one of the most common metabolic diseases worldwide, reducing the qualityAbstract
Ushbu tezis 2-turi qandli diabet (T2DM) bilan og‘rigan bemorlarda ichak mikrobiotasi tarkibining biokimyoviy ko‘rsatkichlarga ta’sirini o‘rganishga bag‘ishlangan. Tadqiqotda ichak mikrobiotasining disbiozi (muvozanat buzilishi), xususan, Firmicutes va Bacteroidetes nisbati o‘zgarishi, butirat ishlab chiqaruvchi bakteriyalar (Akkermansia muciniphila, Faecalibacterium prausnitzii, Roseburia va boshqalar) kamayishi, shuningdek, opportunistik patogenlar (Escherichia coli, Lactobacillus ayrim turlari, Bacteroides vulgatus) ko‘payishi T2DM patogenezida muhim rol o‘ynashi ko‘rsatilgan..Natijalar kasallikni oldini olish va davolashda mikrobiotani modulyatsiya qilishning ahamiyatini ta’kidlaydi.
References
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