EFFECTIVENESS OF PRF MEMBRANES IN THE REGENERATION OF BONE DEFECTS IN PERIODONTITIS
Keywords:
PRF (Platelet-Rich Fibrin), Periodontitis, Bone defect, Regeneration, Osteogenesis, Biological membrane.Abstract
This thesis examines the effectiveness of PRF membranes (Platelet-Rich Fibrin) in the regeneration of bone defects in periodontitis. PRF is prepared from the patient’s own blood and possesses high biological activity, promoting osteogenesis, accelerating soft tissue healing, and reducing inflammatory processes. Clinical data indicate that the use of PRF leads to increased bone density, reduction of periodontal pocket depth, and accelerated periodontal recovery. Due to its autologous nature, PRF is a safe method that does not cause immune reactions. The obtained data confirm the перспективность (promising potential) of PRF application in modern periodontology for the restoration of bone structures and improvement of patients’ quality of life.References
1.Akhter, F. (2025). Assessment of platelet-rich fibrin (PRF) in enhancing periodontal regeneration. Journal of Pharmacy & Bioallied Sciences, 17(Suppl. 2), S1285–S1287.
2.Chen, L., Ding, Y., Cheng, G., & Meng, S. (2021). Use of platelet-rich fibrin in the treatment of periodontal intrabony defects: A systematic review and meta-analysis. BioMed Research International.
3.Miron, R. J., Moraschini, V., Fujioka-Kobayashi, M., et al. (2021). Use of platelet-rich fibrin for the treatment of periodontal intrabony defects: A systematic review and meta-analysis. Clinical Oral Investigations, 25, 2461–2478.
4.Azimova, A. A., Malikov, D. I., & Shaykulov, H. Sh. (2021). Monitoring of the etiological structure of sepsis. Pedagogical Sciences and Teaching Methods, 48, 18–22.
5.Yanova, E. U., Istatova, F. Sh., & Azimova, A. A. (2023). Morphometry of the cortical substance in cerebral microangiopathy. Central Asian Journal of Medical and Natural Science, 4(3), 51–64.
