PREMATURE MYOCARDIAL INFARCTION IN ADULTS AGED 30-40 YEARS: RISK FACTORS, PATHOGENETIC MECHANISMS, AND PREVENTION
Keywords:
myocardial infarction; young adults; premature myocardial infarction; cardiovascular risk factors; endothelial dysfunction; thrombophilia; systemic inflammation; prevention.Abstract
Premature myocardial infarction (MI) in young adults represents an important clinical and public health problem. Although MI has traditionally been associated with older age, acute coronary events increasingly affect individuals of working age, including adults aged 30-40 years. MI occurring at a young age may result in substantial social and economic consequences due to premature disability, loss of working capacity, and an increased risk of recurrent cardiovascular events. The development of MI in this population may involve not only conventional cardiovascular risk factors but also endothelial dysfunction, systemic inflammation, thrombophilic states, psycho-emotional stress, and psychoactive substance use. A better understanding of these factors is therefore essential for improving early diagnosis, risk stratification, and preventive strategies.