LONG-TERM OUTCOMES OF RADICAL SURGICAL TREATMENT IN PATIENTS WITH LOCALLY ADVANCED GASTRIC CANCER

Authors

  • Aziziy A. A Abdikhakimov A. N Abdikhakimov U. N Abdikhakimova M. I Aliev R. A. Gafur-Okhunov M. A Kasymov A. A Mirzaev Kh. M Mutalov Kh. I Shukurova M. A Yusupbekov A. A Ergashev Sh. K Department of Oncology, Oncohematology and Radiation Oncology, Tashkent State Medical University, Tashkent, Uzbekistan Tashkent Regional Branch, Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology, Tashkent, Uzbekistan Department of Oncology, Center for Professional Development of Medical Workers, Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan 4.Ezgu Niyat Private Medical Clinic, Tashkent, Uzbekistan Department of Hematology and Transfusiology, Central Asian University (CAU), Tashkent, Uzbekistan Scientific and Practical Center of Pediatric Oncology, Hematology and Immunology, Tashkent, Uzbekistan Author

Keywords:

Gastric cancer; radical surgery; long-term survival; gastrectomy; clinicopathological factors; prognosis; immunohistochemistry.

Abstract

Gastric cancer remains one of the leading causes of cancer-related mortality worldwide despite significant advances in diagnostic and therapeutic approaches. Radical surgery continues to be the cornerstone of curative treatment for locally advanced gastric cancer (LAGC). However, long-term survival after radical treatment varies considerably among patients with similar TNM stages, suggesting that conventional staging systems alone are insufficient for accurate prognostic assessment. Evaluation of clinicopathological characteristics associated with prolonged survival is essential for optimizing surgical strategies, improving individualized treatment planning, and identifying patients with favorable biological tumor behavior. The analysis of patients who survive more than 10 years after radical treatment represents a unique opportunity to identify prognostic factors influencing long-term outcomes.

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Published

2026-08-06

Issue

Vol. 6 No. 02 (2026): Scottish International Conference on Multidisciplinary Research and Innovation (SICMRI 2026)

Section

Articles